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Fildena 50 mg works by blocking the PDE-5 enzyme. This enzyme normally restricts blood flow in the penile blood vessels. When it is inhibited, the blood vessels relax and widen, allowing better circulation during sexual arousal. However, the medicine does not create an erection on its own—sexual stimulation is required for it to work effectively. This dose is considered a standard starting strength for many men. It is usually taken 30 to 60 minutes before sexual activity with a glass of water. Its effects generally last for about 4 to 6 hours, although this may vary depending on age, metabolism, health condition, and diet.

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